O-PCM, or Ortho-Phenylcyclohexylmorpholine, is a synthetic arylcyclohexylamine derivative that is studied primarily for its dissociative and NMDA receptor antagonistic properties. Structurally related to compounds like PCP and 3-MeO-PCP, O-PCM introduces a morpholine ring to the base arylcyclohexyl structure, potentially influencing both its pharmacokinetics and pharmacodynamics. It is not approved for human consumption and is strictly distributed for analytical and laboratory-based research.

• Chemical Classification: O-PCM belongs to the arylcyclohexylamine class, known for its strong interaction with NMDA receptors, contributing to dissociative and anesthetic-like effects in animal models and receptor-binding simulations.

• Research Use Only: This compound is strictly sold for laboratory or forensic research. It is not intended for human use, therapeutic application, or recreational experimentation.

• Structural Characteristics: The morpholine ring in O-PCM distinguishes it from more conventional PCP analogues, likely modifying receptor affinity and lipid solubility.

• Potential Applications: O-PCM is used in receptor mapping, neurochemical signaling analysis, and comparative behavioral studies alongside similar compounds.

• Novelty and Scarcity: As a lesser-known research chemical, O-PCM presents a unique opportunity for early-stage study into emerging dissociative structures with NMDA antagonism.

The legal status of O-PCM varies by jurisdiction, as it is a novel compound that may not yet be explicitly scheduled under international or national drug control laws. However, it is essential to understand the implications of analogue laws and compound classification under controlled substance analogues.

• Not Specifically Scheduled: In most countries, O-PCM is not yet explicitly listed as a controlled substance, allowing for legal sale and distribution for research purposes.

• Subject to Analogue Laws: Certain countries, including the United States and parts of Europe, apply analogue legislation which could classify O-PCM as an illicit substance if intended for human consumption.

• Research Use Clause: RC Plug only sells O-PCM for legitimate scientific or analytical research. Purchasers must confirm it will not be used for human ingestion or therapeutic purposes.

• Restricted Regions: We do not ship O-PCM to locations where analogues of PCP or dissociatives are banned by default, such as some states in the U.S., certain EU countries, and jurisdictions with blanket analogues regulations.

• Due Diligence Encouraged: We advise researchers to check with their local legal and compliance teams before ordering to avoid import or possession violations.

• Compliance Documentation: Upon request, we can provide chemical documentation such as COA and SDS to support lawful acquisition for research entities.

O-PCM’s structural and functional characteristics make it an important tool in neuropharmacological, toxicological, and receptor-binding research. It is studied for its NMDA antagonism and potential to shed light on novel dissociative mechanisms.

• NMDA Receptor Studies: Like PCP and ketamine, O-PCM is believed to block NMDA receptors, a property central to research on dissociation, neuroplasticity, and cognitive interruption.

• Behavioral Pharmacology: Researchers often use compounds like O-PCM in rodent studies to evaluate locomotor disruption, pain response modulation, or anesthetic profiles.

• Neurochemical Mapping: It serves as a comparative tool in mapping synaptic transmission, helping scientists understand how morpholine-modified dissociatives interact with neural circuits.

• SAR (Structure-Activity Relationship): As a novel structure, O-PCM offers a unique branch in SAR studies aimed at correlating structural changes with changes in pharmacological effect.

• Toxicological Profiling: Labs engaged in forensic science or toxicology may test O-PCM to establish its breakdown pathways, toxicity markers, or postmortem identification profiles.

Proper storage of O-PCM is essential to preserve its stability, purity, and effectiveness as a reference material. Like most fine chemicals, O-PCM is sensitive to environmental factors such as temperature, light, and moisture.

• Temperature Control: O-PCM should be stored in a freezer at or below -20°C to maintain chemical integrity over extended periods.

• Light Protection: Exposure to UV or direct sunlight can degrade the compound’s structure over time. Opaque or amber vials are recommended for storage.

• Moisture Avoidance: The compound must remain in a dry environment. Hygroscopic contamination can alter the weight and reduce purity.

• Sealed Packaging: Keep the product in its original, airtight container until use to prevent exposure to air, contaminants, or oxidizing agents.

• Avoid Frequent Opening: Repeated exposure to ambient air when opening and resealing the vial can accelerate degradation or contamination risk.

• Short-Term Storage: If short-term refrigeration is the only available option, ensure it is sealed and used within a limited time window.

• Proper Labeling: Labs should ensure all containers are labeled with date of receipt, storage conditions, and hazard information to prevent mishandling.

We pride ourselves on offering O-PCM that meets the highest standards of laboratory-grade chemical research. Purity directly influences reproducibility, which is why our O-PCM is thoroughly tested and verified before release.

• ≥98% Laboratory-Grade Purity: All O-PCM we offer meets or exceeds 98% purity, confirmed through advanced techniques such as HPLC and NMR.

• Third-Party Lab Tested: Every batch is independently verified to avoid bias and ensure compliance with scientific standards.

• Batch Consistency: We maintain strict synthesis protocols and batch tracking to ensure each delivery is consistent with the previous one.

• Full Documentation Supplied: Each unit includes a Certificate of Analysis (COA) and Safety Data Sheet (SDS). Upon request, we also provide detailed NMR or mass spec data.

• Contamination-Free: Packaging and handling follow GMP-like lab practices to ensure no cross-contamination from other compounds.

• Post-Shipment Stability: We validate our packaging methods to guarantee that purity levels remain stable during standard international transit.

O-PCM is not approved for in vivo studies involving humans or animals intended for therapeutic or diagnostic purposes. Although structurally similar to some anesthetics and dissociatives, O-PCM is classified strictly for analytical, forensic, and in vitro laboratory research. Researchers must adhere to institutional and legal guidelines when handling such compounds.

• Not for Human Consumption: O-PCM is not approved for ingestion, injection, or any route of administration in humans under any circumstances. Doing so violates our terms and international chemical safety regulations.

• In Vitro Research Only: The intended use is confined to in vitro systems such as receptor binding assays, structural interaction modeling, or cell-line toxicology analysis.

• Restricted by Ethical Regulations: In many countries, research ethics boards do not permit in vivo testing on animals without prior safety evaluations, which O-PCM has not undergone.

• Potential Liability: Unauthorized in vivo use can expose institutions or researchers to legal consequences and funding penalties, particularly under analogue acts or chemical misuse statutes.

• No Clinical Data Available: There is currently no formal toxicological or pharmacokinetic profile established for O-PCM in living organisms, making it unsuitable for physiological experimentation.

• RC Plug’ Policy: We do not condone or supply O-PCM for any experiment involving humans or live animal subjects. All buyers must agree to this upon purchase.

O-PCM shares a similar backbone with PCP and 3-MeO-PCP but includes a morpholine ring substitution, which changes its receptor interaction and potentially alters its onset, intensity, and side-effect profile in receptor models. These differences make O-PCM valuable for comparative studies in the field of neuropsychopharmacology.

• Receptor Profile Variability: While all three compounds are NMDA antagonists, O-PCM’s morpholine ring may influence its affinity for off-target receptors like dopamine or sigma receptors, altering its spectrum of effects.

• Potency and Duration: Anecdotal and preliminary in vitro reports suggest O-PCM has moderate to high potency, with a 4–6 hour duration, falling between PCP (longer) and 3-MeO-PCP (moderate).

• Structural Novelty: O-PCM’s morpholine component gives it distinct metabolic and solubility traits that set it apart from more traditional arylcyclohexylamines.

• Side-Effect Profile (Potential): Structural analogues with morpholine substitutions often display reduced excitotoxicity in some studies, though no definitive in vivo results exist for O-PCM.

• Value in Comparative Research: O-PCM helps researchers understand how minor substitutions in a well-known backbone (PCP) can yield different pharmacological and physiological effects.

• Synthesis and Stability: Compared to PCP, O-PCM is more difficult to synthesize but has demonstrated similar or better thermal and chemical stability in sealed conditions.

No, O-PCM is not water-soluble. Its chemical structure favors organic solvents, which should be carefully selected for dissolution in laboratory use. Incorrect solvent handling can lead to ineffective experiments or inconsistent results.

• Preferred Solvents: O-PCM is highly soluble in organic solvents such as ethanol, dimethyl sulfoxide (DMSO), acetone, and methanol. These solvents maintain compound stability and allow for controlled dosing in research setups.

• Avoid Aqueous Solutions: Due to its hydrophobic nature and complex molecular structure, O-PCM has minimal solubility in water and aqueous buffers, which can lead to clumping or uneven distribution.

• Solution Stability: When dissolved in proper solvents and stored in amber vials at low temperatures, O-PCM maintains chemical stability over weeks.

• Recommended Concentration: Researchers often prepare stock solutions at 1–10 mg/mL in DMSO or ethanol, depending on experimental needs.

• Sterility Consideration: Solvents used should be filtered using 0.22μm filters for sterile applications to prevent microbial contamination.

• Glassware Use Only: Plastic can sometimes absorb or react with organic solvents—glass vials and pipettes are the preferred medium when handling O-PCM.

O-PCM is known for its high chemical stability under proper storage conditions. When sealed, kept away from light, and refrigerated, it retains structural integrity for extended durations, making it a dependable research standard.

• Stable for 24 Months: When stored in a freezer at -20°C in its original sealed packaging, O-PCM maintains purity for up to two years without measurable degradation.

• Temperature Sensitivity: Exposure to high heat can lead to decomposition, altering the molecular weight and diminishing potency.

• UV Sensitivity: O-PCM is susceptible to photodegradation. It must be stored in amber vials or opaque containers to avoid structural breakdown.

• Moisture Control: Hygroscopic interference (from humidity or water) can lead to hydrolysis or clumping, impacting solubility and assay reliability.

• Air Exposure Risks: Repeated opening of the storage container can expose the sample to oxygen, leading to slow oxidation over time.

• Post-Dissolution Stability: Once dissolved in solvent, it should be used within 2–3 weeks unless frozen, as chemical integrity may diminish in solution form.

O-PCM is not detected in most standard toxicology or drug screening panels, making it a subject of interest in forensic and advanced analytical research. Specialized equipment and protocols are required to identify its presence in biological or chemical samples.

• Undetectable in Basic Drug Panels: O-PCM is absent from standard 5-panel and 10-panel drug tests, which screen for common narcotics, not novel dissociatives.

• Requires Advanced Techniques: Detection typically involves GC-MS (Gas Chromatography–Mass Spectrometry), LC-MS/MS, or NMR spectroscopy.

• No Immunoassay Cross-Reactivity: Its unique structure doesn’t generally trigger false positives in enzyme-linked immunoassays (ELISAs), commonly used in workplace or probation testing.

• Forensic Identification: In forensic toxicology, custom calibration and database entries must be created to accurately detect O-PCM in fluids or tissues.

• Metabolite Uncertainty: Because the metabolic pathway of O-PCM is not well-studied, metabolite identification may be more complex than other arylcyclohexylamines.

• Utility in Stealth Research: The compound’s detection resistance makes it valuable in studies of emerging psychoactives, aiding the development of future screening protocols.

Yes, we provide comprehensive documentation with every unit of O-PCM to ensure transparency, reproducibility, and quality assurance in your research. This documentation helps confirm the identity, purity, and safe handling of the compound, which is critical for scientific validation and compliance purposes.

• Certificate of Analysis (COA): Every batch comes with a COA that verifies the purity (typically ≥98%), molecular structure, and analytical methods used during testing such as HPLC or NMR.

• Safety Data Sheet (SDS/MSDS): The SDS outlines essential information including hazard identification, storage protocols, first aid measures, handling instructions, and regulatory compliance status.

• Batch-Specific Data: Each product label includes batch numbers and synthesis dates to facilitate traceability and ensure uniformity across research experiments.

• Optional NMR or LC-MS Reports: Upon request, we can provide advanced analytical documentation such as Nuclear Magnetic Resonance or Liquid Chromatography–Mass Spectrometry spectra.

• Regulatory Use Statements: All documents clearly state that O-PCM is for research use only and not for human or veterinary application.

• Digital and Physical Formats: Documentation is included with your shipment and can also be sent via email upon request for archival or submission purposes.

We cater to both small-scale researchers and large institutional buyers, so we do not impose a strict minimum order quantity for O-PCM. Whether you need a few milligrams for assay testing or several grams for extended research, we provide flexible purchase options.

• No Minimum Threshold: You can order as little as 100mg, which is ideal for early-stage evaluations, solubility tests, or pilot screening.

• Scalable Options: We offer quantities in 100mg, 250mg, 500mg, 1g, 2g, 5g, and custom bulk packages—depending on your research needs.

• Bulk Pricing Discounts: Volume discounts apply for quantities above 2g, and we’re happy to quote custom rates for institutions, universities, or recurring orders.

• Custom Weight Requests: We can supply non-standard quantities upon request, with lab-verified measurements and tamper-proof packaging.

• No Subscription Required: You can purchase on demand without setting up a recurring schedule or service agreement.

• Fast Dispatch Regardless of Quantity: Whether you order 100mg or 10g, your shipment is processed with the same priority and care.

Yes, discreet shipping is a cornerstone of our service, particularly for compounds like O-PCM. We understand the sensitivity involved in handling research chemicals, and we take every measure to protect your privacy and ensure safe, undetectable delivery.

• Unmarked Packaging: All shipments are packed in plain, nondescript materials with no branding, logos, or product references on the outside.

• Stealth Layering: We use multiple inner layers (heat-sealed bags, vials, and foil shielding) to prevent detection via X-ray or manual inspection.

• No Chemical Names Listed: The shipping label and customs declaration use neutral, generic descriptions like “lab sample” or “industrial standard,” not the compound name.

• Odor-Resistant and Moisture-Proof: Our packaging materials are resistant to both environmental factors and potential detection by customs dogs.

• Signature-Free Delivery: For privacy, most shipments do not require signature upon delivery unless requested by the buyer or required by courier service.

• Stealth Replacements Available: If you’re in a high-risk region or have special handling needs, we offer alternative packaging formats on request for added protection.

Yes, based on structural similarity and anecdotal reports, O-PCM is considered a dissociative compound with psychoactive potential, but it is not approved or legal for human consumption. Its psychoactive profile is inferred from its interaction with NMDA receptors, which mediate dissociation, altered perception, and cognitive modulation in known analogues.

• NMDA Receptor Antagonism: Like PCP and ketamine, O-PCM blocks NMDA receptors, disrupting excitatory glutamate signaling and inducing dissociative-like states in animal or computational models.

• Unverified Psychoactivity in Humans: While its chemical structure suggests psychoactive potential, no clinical studies have formally documented its effects in humans.

• Not Approved for Use: Any attempt to consume, inhale, or inject O-PCM would be dangerous and illegal under research-use-only terms.

• Potential Behavioral Modulation: In silico and receptor affinity studies suggest potential effects on perception, memory, and coordination—similar to other arylcyclohexylamines.

• No Pharmacokinetic Data: Without proper metabolism, absorption, distribution, or elimination studies, the true extent and profile of psychoactivity remains unknown.

• Legal Consequences of Use: Possession or use of O-PCM as a psychoactive substance may result in legal actions under analogue drug laws in many jurisdictions.

Handling O-PCM in the lab requires strict adherence to chemical safety practices, even though it may appear stable in appearance. Because it is a novel compound with poorly understood toxicity, researchers must take extra care in limiting exposure and preventing contamination.

• Personal Protective Equipment (PPE): Always wear gloves (nitrile recommended), lab coats, and protective eyewear when handling the compound to prevent skin or eye contact.

• Fume Hood Use: Work in a chemical fume hood or well-ventilated area to avoid inhaling any accidental dust or vapors during weighing or dilution.

• Proper Storage and Labeling: Store O-PCM in a sealed, labeled container at -20°C, away from oxidizing agents or volatile chemicals.

• No Food or Drink Nearby: Never handle or store O-PCM near consumables or personal belongings, and avoid hand-to-face contact until gloves are removed.

• Dedicated Equipment: Use separate glassware and tools for handling O-PCM to avoid cross-contamination with other chemicals or experiments.

• Spill Response: In case of a spill, use inert absorbent material and dispose of it according to chemical waste guidelines. Ventilate the area immediately.

• Institutional Oversight: Ensure your facility has reviewed and approved the handling of novel arylcyclohexylamines and that all personnel are trained in emergency protocols.

Yes, O-PCM can be exported to many countries, but strict compliance with international shipping laws, import regulations, and chemical classification is required. At RC Plug, we ensure that all shipments conform to both the origin and destination country’s requirements to avoid legal or customs issues.

• Global Shipping Availability: We ship to most research-permitting countries worldwide, including Europe, Asia, North America, and selected South American and Oceanic countries.

• Legal Compliance Required: Buyers are responsible for understanding their local import laws. Some jurisdictions may classify O-PCM under analogue or psychoactive substance regulations.

• Discreet Export Practices: We use stealth packaging techniques and neutral declarations to avoid unnecessary scrutiny during customs clearance.

• Documentation for Customs: Upon request, we can include invoices marked for “research purposes,” COA, SDS, and batch ID documents to assist with smooth customs processing.

• Restricted Territories: We do not export to countries where arylcyclohexylamines or structurally similar compounds are explicitly banned or carry high legal risk.

• Customs Clearance Responsibility: While we assist with documentation, the customer bears responsibility for confirming legality in their country and resolving customs delays if they occur.