MXPr, also known as Methoxpropamine or 3-MeO-2′-oxo-PCPr, is a dissociative arylcyclohexylamine compound structurally related to MXE and ketamine. In the context of research, MXPr is primarily used in neurochemical, pharmacodynamic, and psychopharmacological studies due to its ability to antagonize NMDA receptors. It is not approved for clinical or therapeutic use and is classified strictly as a research chemical.

• NMDA Receptor Antagonism: MXPr functions as an NMDA (N-methyl-D-aspartate) receptor antagonist, making it suitable for studying glutamatergic system modulation and excitatory neurotransmission pathways in neurological research.

• Behavioral and Cognitive Modeling: MXPr is often used in experimental models exploring dissociative states, altered cognition, and behavioral detachment, aiding in the study of consciousness and perception in controlled environments.

• Structure-Activity Relationship (SAR) Studies: Researchers utilize MXPr to compare and contrast its structural influence with similar compounds like MXE or ketamine, contributing to SAR profiling within the arylcyclohexylamine class.

• Pharmacokinetic Profiling: MXPr is a valuable tool for assessing absorption, distribution, metabolism, and excretion (ADME) characteristics within novel dissociative compounds.

• In Vitro Binding Assays: Its ability to interact with receptor subtypes in vitro makes it suitable for lab-based receptor mapping and pharmacological pathway exploration.

• Receptor Selectivity Studies: MXPr is studied to assess its specificity for NMDA receptors compared to off-target effects on dopamine, serotonin, or opioid receptors.

• Non-Medical Exploratory Use: Although not permitted for human consumption, MXPr is discussed in academic circles for its comparative effectiveness in producing dissociation with reduced sedation versus classical anesthetics.

MXPr presents a unique dissociative profile that is often described as a midpoint between MXE and ketamine in both effect intensity and duration. Researchers are particularly interested in how MXPr modifies cognitive processes and perception differently from its analogs while maintaining similar pharmacological targets.

• Duration of Action: MXPr typically lasts 3–6 hours, which is longer than ketamine (1–2 hours) but shorter than MXE (up to 8 hours). This moderate duration allows more manageable timeframes for structured experimentation.

• Mental Clarity vs. Disruption: Anecdotal research notes MXPr provides clearer cognitive awareness compared to MXE, which is often associated with stronger emotional shifts and confusion. This makes MXPr suitable for subtle cognitive effect analysis.

• Potency Spectrum: MXPr is considered moderately potent — less intense than MXE but with more pronounced dissociative depth than ketamine. This balance makes it useful in dose-dependent response experiments.

• Sedation Profile: MXPr induces less physical sedation than ketamine or MXE, making it easier to observe isolated dissociative effects without confounding motor suppression.

• Mechanistic Similarities: All three compounds share NMDA receptor antagonism, but MXPr may have a reduced impact on dopamine reuptake or sigma receptors compared to ketamine, aiding receptor-selectivity studies.

• Legal and Scheduling Differences: MXPr remains unscheduled in many countries, offering fewer regulatory barriers to procurement compared to the tightly controlled status of ketamine and the increasingly restricted access to MXE.

• Structure-Based Differentiation: While ketamine includes a chlorine atom and MXE features an ethylated morpholine, MXPr’s methoxy substitution and cyclohexyl-piperidinone core yield distinct molecular behavior in receptor interaction studies.

MXPr is currently legal and unscheduled in many jurisdictions, particularly when acquired and used strictly for research purposes. However, its legal status can vary significantly based on region and evolving regulatory frameworks. Researchers are responsible for understanding and complying with their local laws.

• Unscheduled in Most Regions: As of now, MXPr is not listed under the Controlled Substances Acts of many countries, including the United States and several EU nations, which allows for legal research possession and ordering.

• Research-Only Designation: RC Plug supplies MXPr solely for analytical, forensic, or scientific research. It is not intended for human or veterinary use under any jurisdiction.

• Risk of Analog Laws: In countries with broad analogue legislation, such as the U.S. Federal Analogue Act, MXPr could be considered an analogue of MXE or ketamine, depending on intent and jurisdictional interpretation.

• Import and Customs Restrictions: Some countries may restrict importation regardless of scheduling. It’s essential to verify shipping eligibility before placing an order.

• No Prescription Required: Due to its classification as a non-medical research compound, MXPr can be purchased from RC Plug without a prescription or pharmacy license.

• Compliance-Focused Shipping: We package MXPr discreetly and in compliance with international regulations to reduce customs flags and shipping delays.

• Always Check Local Law: We strongly encourage all buyers to consult local, state, or federal authorities or legal advisors before purchasing to ensure full compliance with applicable law.

Proper storage of MXPr is crucial to preserving its stability, potency, and molecular integrity. Like many research chemicals, exposure to moisture, light, and temperature fluctuations can accelerate degradation and compromise research validity.

• Temperature Control: Store MXPr in a cool environment, ideally between 15–25°C. Avoid extreme heat or cold, which can cause molecular breakdown or condensation within the container.

• Dry Storage Environment: Always store the compound in a moisture-free area. Humidity can lead to clumping, loss of potency, and contamination.

• Protect from Light: Use amber or opaque containers to shield MXPr from ultraviolet (UV) and visible light, which can initiate photochemical reactions that alter the compound’s properties.

• Air-Tight Sealing: Reseal the product immediately after use. Exposure to oxygen can result in slow oxidation, impacting the purity and effectiveness of the compound.

• Avoid Frequent Handling: Limit repeated exposure to air, heat, or moisture by dividing large quantities into smaller, use-ready containers if needed.

• Use Desiccants: For long-term storage, include silica gel or other moisture-absorbing packets inside the storage container to maintain dryness.

• Label Clearly: Properly label containers with chemical name, batch number, and date received to ensure traceability and prevent cross-contamination in multi-compound labs.

Yes. RC Plug provides a complete tracking experience for all MXPr purchases to ensure transparency, delivery assurance, and peace of mind. Once your order is dispatched, tracking becomes immediately available via your email.

• Tracking Number Issued Post-Purchase: As soon as your order is processed and shipped, we generate and email a unique tracking number linked to your selected courier.

• Real-Time Monitoring: You can follow your order’s progress through every shipping milestone — from dispatch, customs clearance, to final delivery — using the provided tracking link.

• Courier Transparency: We partner with reliable, internationally recognized couriers to support fast and secure deliveries with active tracking systems.

• Discreet Presentation: While trackable, our packages remain fully discreet with no indication of contents, ensuring your privacy is never compromised.

• Customer Support for Updates: If you experience delays, we offer live support to assist with rerouting, investigating hold-ups, or arranging reshipments.

• Shipping Notifications: We send updates at every critical phase — order confirmation, shipment dispatch, and successful delivery.

• Protection Against Loss: If your order is lost or stuck in transit beyond a reasonable timeframe, our 30-day full refund or reshipment policy ensures you are covered.

MXPr, in its research-grade form, is typically supplied as a solid crystalline or fine powder substance. Its physical appearance can vary slightly depending on the batch, processing method, and storage conditions, but it generally maintains a consistent visual profile, aiding in quality verification.

• Color: Most batches of MXPr appear as white to off-white in color. Slight off-white or beige tones may occur due to minute impurities or exposure to light or air but do not necessarily indicate degradation.

• Form: MXPr is most commonly distributed as a crystalline powder or very fine, granulated substance. This makes it suitable for precise measurement and controlled research handling.

• Consistency: High-quality MXPr is smooth in texture and not clumped, indicating proper drying and storage during production. Sticky or clumpy samples may suggest moisture exposure.

• Ease of Handling: The powdered form allows for easier weighing, dissolution, and suspension in various solvents used during lab-based procedures.

• No Fillers or Cutting Agents: At RC Plug, our MXPr is free from any adulterants, fillers, or additives. It’s delivered in its purest research-grade state.

• Visual Identification: Although appearance alone should never be used to verify identity, consistent texture and color contribute to physical QC (Quality Control) assessments in labs.

• Lab Packaging: We supply MXPr in vacuum-sealed, light-resistant pouches that preserve the integrity and appearance of the compound until use.

MXPr can be appropriate for researchers who are new to dissociative pharmacology, provided proper lab procedures, handling techniques, and risk assessments are in place. Its moderate potency and manageable duration make it relatively accessible in structured environments, though it still requires rigorous oversight.

• Moderate Duration: MXPr’s 3–6 hour window of activity offers researchers ample time to observe and document changes without extended commitment or risk of extended exposure.

• Controlled Potency: Unlike more intense dissociatives, MXPr produces a balance of dissociative and cognitive effects that allow for clearer analysis at lower concentrations.

• Less Sedation: Compared to ketamine or MXE, MXPr induces less physical lethargy, which reduces the likelihood of interference with locomotor or motor response studies.

• Straightforward Solubility: MXPr dissolves easily in common laboratory solvents like ethanol or DMSO, making it accessible for chemical preparation and application.

• Standard Safety Guidelines Apply: Like all research chemicals, it must be handled using protective equipment (PPE), precise measurement tools, and within approved lab protocols to avoid accidental exposure or contamination.

• Ethical Considerations: Beginners must adhere to ethical research guidelines, ensuring MXPr is never used outside in-vitro, analytical, or non-consumptive frameworks.

• Supportive Documentation Available: At RC Plug, we provide guidance on safe handling and can offer supporting documentation like Certificates of Analysis for researchers needing extra assurance.

Safe handling of MXPr is critical to maintain lab safety, experimental reliability, and researcher well-being. As with any chemical compound—especially dissociative substances—strict laboratory practices must be followed from opening the package to final disposal.

• Personal Protective Equipment (PPE): Gloves, lab coats, and protective eyewear should always be worn to prevent dermal contact or inhalation of airborne particles.

• Ventilated Environment: Handling MXPr in a fume hood or well-ventilated area reduces the risk of accidental inhalation, especially when transferring or weighing the powder.

• Precision Weighing: Always use a milligram-scale (0.001g precision) to accurately measure doses. Even small inaccuracies can affect experimental outcomes or present risk if misused.

• Isolate Workspace: Use a dedicated, contaminant-free surface or station to prevent cross-contamination with other compounds. Clean workspaces before and after handling.

• Minimize Exposure: Limit the time MXPr is exposed to open air. Quickly reseal containers after retrieving the required amount to preserve chemical integrity.

• Solvent Handling: If dissolving MXPr, use proper solvent-resistant containers and follow chemical compatibility charts to avoid reactions with incompatible materials.

• Waste Disposal: Dispose of MXPr residue, containers, or contaminated materials following local hazardous waste protocols. Never flush down drains or discard with general waste.

Yes, RC Plug provides Certificates of Analysis (COAs) for MXPr upon request. These documents offer critical batch-level data that verifies the compound’s identity, purity, and structural composition—reinforcing our commitment to transparency and research quality.

• Batch-Specific Verification: Each COA is tied to a unique production batch and includes the date of manufacture, analytical method used, and test results.

• Purity Confirmation: Our COAs confirm that the MXPr supplied meets ≥98% purity standards, verified through advanced techniques such as GC-MS (Gas Chromatography-Mass Spectrometry) or HPLC (High-Performance Liquid Chromatography).

• Independent Testing Labs: We partner with certified third-party labs to perform all testing, ensuring unbiased and accurate reporting.

• Request Process: Researchers can request the COA during checkout, or by contacting our support team with the order number after purchase.

• Regulatory Reference: COAs support your institutional recordkeeping, especially if your organization or customs agency requires verification of substance identity for import or internal use.

• Documentation for Academic Use: If your institution or supervisor requires formal confirmation of material specifications, our COAs can serve as supporting documentation for study approval.

• Updated With Every Batch: COAs are regenerated with each new MXPr batch, ensuring the data reflects the most current and accurate findings.

MXPr belongs to the arylcyclohexylamine class of compounds and is structurally defined by its methoxy-phenyl substitution and ketone functional group attached to a piperidine ring. Its structure underlies its pharmacological behavior, particularly in how it interacts with NMDA receptors and other CNS targets.

• Base Structure: MXPr features a cyclohexyl core attached to a phenyl ring substituted with a methoxy group (–OCH₃) at the 3-position. This arrangement contributes to its affinity for NMDA receptor binding sites.

• Ketone Group: The presence of a ketone (oxo) functional group at the 2-position of the piperidine ring classifies it as a 2-oxo-PCPr analogue, similar in arrangement to MXE.

• Piperidine Attachment: This six-membered nitrogen-containing ring contributes to its classification as a dissociative, influencing how it modulates CNS function.

• Molecular Formula: C16H23NO, with a molecular weight of approximately 245.36 g/mol, allowing researchers to calculate molarity for in vitro experimentation.

• Lipid Solubility Implications: The compound’s methoxy and hydrocarbon components give it relatively high lipid solubility, which may influence membrane penetration and receptor access in simulated biological environments.

• Structure-Activity Comparison: Its structural differences from MXE (which includes an ethylated amine) or ketamine (which includes a chlorine atom) provide insight into how minor substitutions affect dissociative intensity and duration.

• Receptor Binding Predictability: The spatial arrangement of functional groups makes MXPr a reliable candidate for NMDA receptor affinity modeling, aiding drug design and psychotropic research.

Solubility is an important factor in determining how a chemical can be prepared, stored, and applied in research. MXPr exhibits characteristics that make it moderately soluble in some environments and highly soluble in others, depending on the solvent used. Understanding its solubility profile ensures proper formulation and handling in laboratory conditions.

• Moderate Water Solubility: MXPr is only partially soluble in water. This limited solubility can pose challenges for water-based assays unless the compound is first dissolved in an organic co-solvent.

• High Lipid Solubility: Due to its aryl and methoxy structure, MXPr has high solubility in lipophilic solvents. This makes it more compatible with organic solvents like ethanol, methanol, DMSO, and acetone.

• Use of Co-Solvents: In experiments requiring aqueous compatibility, researchers often first dissolve MXPr in DMSO or ethanol and then dilute with a water-based medium.

• Preparation Flexibility: The ability to dissolve in multiple solvents supports a wide range of testing environments including neurochemical assays and receptor-binding studies.

• Storage in Solution: If preparing MXPr in solution, it should be stored in dark, air-tight containers under refrigeration to prevent breakdown or evaporation of the solvent.

• Relevance to Bioavailability Models: In pharmacokinetic simulations, lipid solubility is a predictor of blood-brain barrier penetration, which may be studied in computational or receptor modeling environments.

Stability is a critical property in ensuring that MXPr maintains its chemical integrity from the moment it’s produced to the time it’s used in research. Poor storage or exposure to the elements can compromise results and waste valuable materials. Fortunately, when stored correctly, MXPr demonstrates excellent stability.

• Shelf Life of Up to 24 Months: MXPr remains chemically stable for up to two years when stored in a sealed, cool, and dark environment.

• Sensitivity to Heat and Light: High temperatures or exposure to sunlight can accelerate degradation. Decomposition may manifest as discoloration or changes in crystal texture.

• Humidity Risk: Moisture is one of the most damaging elements for MXPr. Exposure to humid conditions can result in clumping, loss of solubility, and potential hydrolysis.

• Best Stored in Original Packaging: RC Plug ships MXPr in vacuum-sealed, UV-resistant pouches that prevent environmental exposure and extend shelf life.

• Oxidation Vulnerability: Repeated exposure to air can lead to oxidative degradation. Reseal containers tightly after each use.

• No Refrigeration Needed for Short-Term Storage: While refrigeration can extend stability, MXPr remains stable at room temperature for short-term use if kept in a dry, dark location.

• Batch Tracking for Quality Control: We recommend labeling containers with open dates and batch numbers to monitor the age and condition of your supply for long-term projects.

While MXPr is structurally related to known dissociatives, there is limited empirical data on its abuse potential. However, based on structural and pharmacological similarities to MXE and ketamine, researchers consider the possibility of psychological reinforcement as a relevant area of study. That said, it remains a substance intended strictly for non-human research applications.

• Lack of Human Clinical Data: There have been no approved clinical studies on MXPr’s potential for addiction or dependency in humans, leaving its long-term impact speculative.

• Related to Habit-Forming Compounds: MXPr shares similarities with compounds like ketamine, which have shown reinforcing properties in both animal models and human misuse cases.

• NMDA Receptor Involvement: Its action as an NMDA antagonist may influence glutamate modulation and dopamine circuits—pathways often implicated in reinforcing behavior.

• Lower Sedation, Lower Abuse Potential: Anecdotal sources suggest MXPr may not produce as euphoric or rewarding an effect as other dissociatives, which could reduce its likelihood of habitual misuse.

• Research Caution Recommended: All experiments involving MXPr should be conducted under strict safety protocols with proper disposal and recordkeeping.

• Not for Consumption: RC Plug does not endorse or permit any human use of MXPr under any circumstance. It is for controlled laboratory research only.

• Tool for Addiction Studies: MXPr may be used in receptor profiling or behavioral modeling to investigate neurobiological factors in addiction and dissociation pathways.

While MXPr is not for human or animal consumption, it is important for researchers to understand the range of quantities commonly used in in-vitro or modeling environments. Dosage in research is tied to assay sensitivity, solvent volume, and the model used, and must always be handled with precise measurement instruments.

• Typical Lab Quantities: Researchers often begin trials with quantities ranging between 5 mg and 50 mg depending on the scope and sensitivity of the test.

• Start with Microgram Doses: When conducting new experiments, especially in neuroreceptor binding or cellular assays, it’s best to begin at microgram or sub-milligram levels and scale up cautiously.

• Weighing Precision: A digital milligram scale with 0.001g sensitivity is essential to ensure reproducibility and avoid overuse of materials.

• Solvent Compatibility: Dissolve MXPr in an appropriate solvent according to the concentration required for the experimental setup (e.g., 1 mg/ml in ethanol).

• Avoid Volume Waste: Only prepare as much solution as is required for immediate use. Long-term storage in liquid form increases degradation risk.

• Document Each Trial: Maintain precise logs of all dosage applications, solvent ratios, and batch numbers to aid in result analysis and reproducibility.

• Use in Closed Systems: Always apply MXPr in sealed or closed experimental systems like well plates, sealed vials, or controlled environmental chambers to minimize exposure and contamination.

Working with MXPr requires precision, control, and proper lab safety equipment. As a research-grade chemical with psychoactive properties, MXPr should never be handled casually or without the correct tools. The right lab setup ensures accuracy in your experiments and protects researchers from exposure.

• Digital Milligram Scale: Accurate to 0.001g or better, this is necessary for weighing small amounts reliably. Calibration should be performed regularly.

• Personal Protective Equipment (PPE): Gloves (preferably nitrile), lab coats, and eye protection are essential when handling any powdered chemical compound.

• Glassware and Solvent-Resistant Containers: Use borosilicate glass or chemically resistant plastics for dissolution and mixing. Avoid containers that may react with solvents.

• Fume Hood or Laminar Flow Cabinet: These ventilated systems help protect researchers from potential airborne particles or vapors during weighing or dissolution.

• Labeling Supplies: All containers, beakers, and sample vials must be clearly labeled with compound name, concentration, and date of preparation.

• Proper Storage Units: Refrigerators or cool cabinets for storing MXPr away from light and moisture; avoid storing with incompatible chemicals.

• Disposal Containers: Have designated waste containers for organic solvent waste and MXPr-contaminated materials. Follow local regulations for hazardous chemical disposal.

At RC Plug, we provide flexible purchasing options for MXPr to accommodate both individual researchers and institutions. Whether you’re running a small-scale assay or a large batch experiment, we ensure you can access the exact quantity needed with fair pricing and consistent quality.

• Minimum Order Quantity: Our standard minimum order for MXPr typically starts at 250 mg. This ensures manageable packaging, accurate labeling, and efficient fulfillment for our operations and for your research needs.

• Flexible Order Increments: We offer customizable weight options (250 mg, 500 mg, 1 g, 2 g, etc.) to match the scale of your experiments. Whether you need a sample size or bulk quantity, we accommodate both.

• No Hard Upper Limit: We allow bulk and repeat orders for MXPr with no defined maximum cap, provided the orders are for legitimate research purposes and meet compliance with international shipping regulations.

• Bulk Pricing Available: For orders exceeding 5 grams or more, we offer volume-based pricing. Researchers or institutions conducting long-term studies can contact us for bulk quotes.

• Same Quality Across Sizes: All order sizes—small or large—are fulfilled from the same high-purity batch, with consistent quality standards.

• Split Shipping Upon Request: For larger orders, we offer the option to split shipments across multiple packages to reduce customs scrutiny or meet institutional intake policies.

• Purchase Restrictions Apply by Region: While we do not impose limits internally, certain destinations may have import restrictions or maximum shipment weights. We advise customers to confirm local regulations before bulk ordering.