4-CAB, known chemically as 4-chloroamphetamine, is a compound of significant interest within neuropharmacological, toxicological, and forensic chemistry studies. It is primarily investigated as a para-substituted amphetamine analogue, with unique chlorine substitution at the para position influencing its interaction with monoamine transporters. Research into 4-CAB provides comparative insights into how structural modifications affect dopaminergic and serotonergic activity.

• Monoamine Transporter Affinity Studies: 4-CAB is analyzed for its affinity toward dopamine (DAT), serotonin (SERT), and norepinephrine (NET) transporters, which are central to psychostimulant function.

• Structure–Activity Relationship (SAR) Exploration: Researchers use 4-CAB to assess how halogen substitutions (like chlorine) influence receptor binding, potency, and efficacy in comparison to other amphetamines.

• Comparative Toxicology: Its effects on neurotoxicity are compared to structurally related stimulants such as 4-MTA and 4-FA, which share similarities in structure but differ in biological impact.

• In Vitro Receptor Screening: 4-CAB is often subjected to receptor binding assays using HEK cells or brain tissue models to examine binding dynamics.

• Model Compound for Novel Analogue Studies: 4-CAB serves as a reference compound when developing and evaluating new substituted amphetamines for psychoactivity profiling.

• Neurochemical Transport Studies: It aids in mapping monoamine transporter dynamics, especially in the context of SERT and DAT competition.

• Synthetic Route Validation: Chemists may use 4-CAB to test or optimize synthetic methodologies for halogenated amphetamines.

• Reference Marker in Forensic Toxicology: In forensic labs, 4-CAB may be used to develop or validate detection techniques for halogenated phenethylamines.

4-CAB is structurally classified within the substituted amphetamines, many of which are known to exhibit central nervous system stimulant effects. While it has not been approved for human use or systematically studied in vivo, its mechanism is believed to involve modulation of monoamine neurotransmitters, particularly dopamine and serotonin. This suggests it likely produces stimulant-like outcomes under laboratory models.

• Amphetamine Backbone Structure: The core structure of 4-CAB is a phenethylamine with an alpha-methyl group, which is a hallmark of central stimulant agents.

• Para-Chlorine Substitution Influence: The chlorine atom at the para-position alters its pharmacokinetics compared to methyl or fluoro analogues but may still preserve stimulant-like receptor activity.

• Monoamine Release or Reuptake Inhibition: Early studies suggest that 4-CAB may function by promoting neurotransmitter release or inhibiting reuptake, a common property of stimulants.

• Observed Hyperlocomotion in Animal Models: Animal studies with similar compounds have demonstrated increased locomotor activity, suggesting excitatory potential.

• Comparison to Known Stimulants: Structurally, it resembles 4-FA and para-chloro-substituted analogues, which have been confirmed to enhance alertness and energy in controlled settings.

• Potential Psychostimulant Effects: Although unconfirmed in clinical models, researchers speculate that 4-CAB likely acts as a psychostimulant based on transporter affinity.

• Useful in CNS Activation Research: It is employed in experiments that examine central nervous system excitatory states, offering insight into stimulant mechanism diversity.

We ensure that every batch of 4-CAB offered through RC Plug is laboratory-grade and independently verified to meet strict purity standards. Our sourcing and testing protocol guarantees consistency, safety, and optimal performance for high-fidelity research applications. This purity level is critical for ensuring experimental reproducibility and data reliability.

• ≥98% Certified Purity: Each lot is confirmed to contain at least 98% active compound, validated by high-performance analytical methods.

• GC-MS and NMR Testing: We employ gas chromatography–mass spectrometry and nuclear magnetic resonance spectroscopy to identify impurities and confirm molecular structure.

• Batch-Specific Analysis: Every product batch is tracked by number, with certificates of analysis (COAs) available upon request to verify purity and composition.

• Free from Biological Contaminants: We ensure the absence of endotoxins, bacteria, or moisture-related degradation during production and packaging.

• No Adulterants or Fillers: Our 4-CAB is not cut, blended, or diluted with other chemicals. It is offered in its pure form for research accuracy.

• Cold-Chain Compliant Packaging: Sealed under inert conditions and shielded from UV light to prevent degradation or contamination during storage and transport.

• Internal Quality Control Standards: All products are assessed under strict SOPs (Standard Operating Procedures) before approval for sale.

The legal classification of 4-CAB varies by jurisdiction, and it is essential for researchers to assess local regulations before placing an order. As of now, 4-CAB is not explicitly listed under most international drug control schedules, but it may still be subject to analogue or blanket legislation in some countries.

• Not Scheduled Internationally: 4-CAB is not specifically scheduled under the United Nations Conventions, making it more widely accessible for research purposes.

• Analog Laws May Apply: In countries like the United States, Canada, and Australia, analogue acts may regulate 4-CAB if deemed similar to controlled amphetamines.

• No Prescription Requirement: At RC Plug, 4-CAB is sold without prescription as it is offered strictly for laboratory and forensic research.

• Research-Only Sale Conditions: All purchases must be for non-human, academic, or scientific use, and buyers must confirm intent upon checkout.

• Customs Clearance Varies by Country: Some regions may still confiscate shipments due to structural resemblance to known stimulants. We advise prior due diligence.

• Protected Packaging for Legal Compliance: We implement stealth shipping and legal documentation to maximize delivery success through customs.

• Consult Local Authorities If Uncertain: Researchers are encouraged to consult legal counsel or national drug enforcement agencies if unclear about regional policies.

4-CAB is typically presented as a fine crystalline powder in its freebase form. This format is highly stable, manageable for precise weighing, and suitable for solubility testing in various organic solvents. Its physical consistency makes it ideal for handling under standard lab safety protocols and for integration into chemical assays.

• Fine Crystalline Powder: This physical form supports accurate mass measurement for microgram-to-gram scale dosing in analytical workflows.

• Freebase Format: The unprotonated form offers greater compatibility with organic solvents like ethanol and DMSO, making it flexible for multiple experimental contexts.

• Dry and Low-Moisture Profile: The powder has low hygroscopicity, reducing the risk of moisture-related degradation or clumping.

• Visually Consistent: It appears as a white to off-white powder with uniform particle size, aiding consistent sample preparation.

• Solvent-Compatible for Chromatography: The freebase form facilitates column chromatography, thin-layer chromatography (TLC), and solvent extraction techniques.

• Sealed and Vacuum-Stabilized: Our products are vacuum-packed with tamper-evident seals to maintain this consistency during shipping and storage.

• Odorless and Inert Appearance: No detectable scent and no reactive behavior under ambient conditions, making it safe for bench-top handling in appropriate settings.

Proper storage of 4-CAB is essential to preserve its chemical integrity and ensure consistent results in analytical or experimental studies. The compound should be kept in a controlled environment that protects it from moisture, temperature fluctuations, and UV exposure. Maintaining its original packaging also plays a key role in extending shelf life and minimizing contamination.

• Store in a Cool Environment (2–8°C): Refrigerated conditions prevent decomposition and maintain molecular stability over extended periods.

• Avoid Direct Sunlight and UV Exposure: Ultraviolet radiation can break down chemical bonds, especially in halogenated amphetamines like 4-CAB.

• Use Airtight, Light-Proof Containers: Dark glass or sealed vacuum pouches are recommended to prevent oxidation and light-triggered degradation.

• Keep Away from Moisture Sources: Humidity can lead to hydrolysis or clumping, altering solubility and purity over time.

• Do Not Freeze the Compound: Although stable, freezing may cause crystallization shifts or packaging stress, leading to potential structural changes.

• Preserve Original Packaging: RC Plug uses vacuum-sealed, desiccant-packed pouches which are ideal for long-term storage without repackaging.

• Label Clearly with Date and Batch: Keeping a record of batch number and storage date supports lab auditing and experimental traceability.

Although 4-CAB shares many characteristics with compounds used in in vivo animal studies, we strictly sell it for in vitro and analytical purposes only. Researchers considering biological models must comply with ethical standards and local regulations, and RC Plug does not endorse or permit human or non-research animal use of this compound.

• Sold Strictly for In Vitro Use: All sales are conditioned on non-biological, laboratory-only applications such as receptor mapping and binding kinetics.

• Ethical Compliance Required: Any extension to in vivo research requires licensing, ethical approval, and rigorous protocol adherence.

• Lack of Safety Data in Live Organisms: There is no publicly available toxicological database confirming long-term safety, LD50, or organ-specific metabolism.

• Potential Neurotoxic Risk: Related analogues have demonstrated serotonergic neurotoxicity in animal models, which raises caution for live testing.

• No Human or Veterinary Clearance: 4-CAB is not approved for use in humans or animals by any health authority worldwide.

• In Vitro Modeling Is the Standard: Current research focuses on cell-based assays, receptor transport inhibition studies, and simulated CNS interactions.

• We Do Not Support Biological Testing: RC Plug will not fulfill orders from customers intending to use 4-CAB in live systems without institutional documentation.

4-CAB demonstrates good solubility in a range of organic solvents, which supports its versatility in laboratory settings, especially for chromatography, spectroscopy, and dissolution testing. Selecting the right solvent depends on the intended experimental method and the compound’s compatibility with assay conditions.

• DMSO (Dimethyl Sulfoxide): Offers strong solvency with minimal reactivity, making it ideal for stock solutions in biochemical assays.

• Ethanol (≥95%): A widely used organic solvent that supports mid-polarity interactions; compatible with UV-visible spectroscopy and pharmacokinetic testing.

• Acetone and Acetonitrile: Effective for chromatography preparation and solute dispersion in HPLC/GC settings.

• Ethyl Acetate: Suitable for extraction procedures and organic partitioning tasks.

• Chloroform or Dichloromethane (DCM): Used in specific organic chemistry and partition coefficient studies, although proper fume hood use is mandatory.

• Not Water Soluble: Due to its non-polar structure, 4-CAB does not dissolve efficiently in water, which may limit its use in aqueous environments.

• Pre-Filtration Recommended: Regardless of solvent, filtering stock solutions through 0.22 µm membranes ensures assay integrity and prevents particulates from interfering with results.

Yes, at RC Plug we uphold full transparency and support for scientific rigor by providing batch-specific laboratory documentation for 4-CAB and all other products. This ensures researchers have verifiable data for publication, protocol design, or peer review.

• Certificate of Analysis (COA): Available upon request, includes purity, testing methods, and analytical results.

• Batch Number Traceability: Every package is labeled with a unique batch code to connect your product with its specific test results.

• Spectral Data on Request: We can provide NMR, FTIR, or GC-MS scans to confirm identity and rule out impurities.

• Consistency Verification: Our internal logs ensure consistency across batches, minimizing variation for repeated experiments.

• Lab-Validated Results: All testing is conducted by certified third-party laboratories or by our internal analytical team under SOP standards.

• Secure Document Transmission: COAs and supporting documents are sent in encrypted format to ensure confidentiality and security.

• Additional Specifications Upon Approval: For universities or institutions with compliance requirements, we provide supplementary documentation as needed.

Shipping speed for 4-CAB orders depends on your location and the shipping method selected at checkout. At RC Plug, we prioritize speed and stealth to ensure your order arrives promptly and without complications. Orders are processed immediately upon payment confirmation, with tracking provided for complete visibility throughout the delivery cycle.

• Processing Time Within 12–24 Hours: Once your payment is confirmed, we package and dispatch the order within one business day.

• Express Shipping (1–3 Days): Available for customers in the United States, Canada, the EU, and select Asian regions. It’s our fastest and most popular delivery method.

• Standard Shipping (3–7 Days): A more economical option with reliable timelines. Perfect for non-urgent bulk shipments and extended research planning.

• Tracking Number Provided Promptly: We send a tracking ID by email within 12 hours of processing, so you can follow your order’s journey in real time.

• Discreet Courier Networks: We partner with reputable international couriers trained in stealth delivery methods to reduce the risk of delay or inspection.

• Weekend or Holiday Exceptions: Orders placed during weekends or on public holidays will ship on the next business day, which may impact arrival time slightly.

• Optional Same-Day Dispatch for Urgent Orders: Available upon request and based on time zone cut-off—ideal for institutional labs needing immediate material.

RC Plug provides flexible quantity tiers for 4-CAB to suit a range of research needs, from initial compound screening to extensive biochemical modeling. All units are professionally weighed and sealed in tamper-proof, lab-grade packaging.

• Entry-Level (250 mg): Ideal for preliminary structure analysis, microassays, and pilot receptor binding studies.

• Standard Laboratory Use (500 mg – 1 g): Supports medium-scale screening, solubility profiling, and high-precision LC-MS testing.

• Bulk Research Orders (5 g – 10 g): Suitable for large academic institutions or corporate R&D facilities conducting long-term or comparative studies.

• Custom Quantities Available: We accommodate requests for specialized weights or volumes, including multi-batch orders with staggered delivery.

• All Quantities Vacuum-Sealed: Each unit is protected with industrial sealing and serialized labeling to maintain integrity and traceability.

• Consistent Pricing Tiers: Discounts apply progressively for larger quantities without sacrificing quality or packaging standards.

• Pre-Weighed for Accuracy: We use calibrated balances to ensure accuracy within ±0.01 g, with independent verification of critical weights upon request.

No, we currently do not accept credit card payments for any of our products, including 4-CAB. This decision is based on a commitment to customer privacy, financial discretion, and minimizing third-party interference in transactions related to research chemicals.

• No Credit Card Support: Credit card processors impose restrictions on research chemical transactions, and we avoid platforms that could compromise our clients’ discretion.

• Bitcoin (BTC): The most popular option—offering decentralized, encrypted payments with global reach and fast confirmation.

• Zelle: Available to customers in the United States; a fast and convenient peer-to-peer payment option.

• CashApp: Easy-to-use platform offering instant transfers with minimal documentation or delay.

• Bank Transfer (Domestic & International): Reliable method for institutions or bulk orders, with banking instructions provided during checkout.

• Western Union: Acceptable for international customers who prefer offline payments, especially in regions with limited banking access.

• Why No Cards?: Credit card payments expose sensitive billing information, increase fraud risk, and introduce unnecessary bureaucracy into research procurement.

At RC Plug, we have proactive measures in place to minimize the risk of customs seizure. However, in the unlikely event your 4-CAB order is seized, we offer full buyer protection through our reship or refund policy—a cornerstone of our 100% satisfaction guarantee.

• One-Time Free Reshipment: If your package is intercepted or held by customs, we will reship it at no additional charge.

• Full Refund Option: If reshipping is not viable, we’ll process a refund within 3 business days after confirmation of seizure documentation.

• Discrete Packaging to Prevent Seizure: We use stealth techniques such as non-descript outer wrapping, decoy labeling, and tamper-proof inner seals.

• Instructions for Claiming: Customers must provide a copy of the seizure notice or delivery failure notification from the courier to initiate compensation.

• No Need to Return Original Package: In most cases, we do not require the seized package to be returned, simplifying the process.

• High Success Rate: Our stealth shipping methodology has yielded over 95% successful international delivery rates.

• Dedicated Support Team: A dedicated claims team will guide you through reshipment or refund requests quickly and professionally.

Yes, RC Plug offers tiered discounts for customers purchasing 4-CAB in larger volumes. These discounts are structured to support academic institutions, industrial labs, and recurring research partners with better pricing while maintaining premium product standards.

• 5% Off Orders Above 5g: Ideal for teams engaged in multi-phase research or multi-instrument testing.

• 10% Off Orders Above 10g: Offered to institutional buyers conducting large-scale neuropharmacological mapping.

• Custom Pricing for >50g: Bulk order quotations are available upon request, tailored for pharmaceutical companies or universities.

• Loyalty Discounts for Returning Customers: Repeat clients benefit from ongoing access to discount codes and seasonal promotions.

• Flexible Invoicing and Payment Terms: For qualified institutions, we offer invoice-based payment schedules and deferred billing cycles.

• Combined Bulk Discount for Multi-Product Orders: You can mix 4-CAB with other research compounds and still qualify for cumulative discounts.

• Special Grants or Departmental Budgets: For educational institutions, we provide support letters and special rates to facilitate departmental purchase approval.

At RC Plug, we do not impose a strict minimum purchase requirement for 4-CAB or any of our products. Whether you’re a solo researcher testing micromolar concentrations or a lab needing grams of material, we cater to all scales of operation. However, our pricing and shipping discounts are structured to reward larger purchases.

• No Mandatory Minimum Order: You can order even 250 mg of 4-CAB without restriction, ideal for exploratory or pilot studies.

• Recommended Minimum for Economic Shipping: Orders over $150 often qualify for shipping discounts or free express upgrades.

• Bulk Orders Benefit from Tiered Discounts: Larger quantities (5g, 10g, etc.) not only reduce per-gram cost but improve shipment value.

• All Orders Receive Same Discreet Packaging: Whether small or large, each order is handled with the same secure, odor-proof, and tamper-sealed process.

• Flexible for Academic Labs and Individual Researchers: We serve institutions and independent scientists equally, with no account minimums required.

• No Additional Handling Charges for Small Orders: Pricing includes fulfillment, packaging, and tracking services regardless of order size.

• Invoicing Available for Larger Institutional Orders: Departments with purchasing protocols can request invoicing even for small test quantities.